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Search Results for " factor B "

阻害剤

天然化合物

416

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T38969	Factor B-IN-1
	Factor B-IN-1 is a Factor B inhibitor.
TP2234	Coagulation factor II (thrombin) B chain fragment [Homo sapiens]		Others
	Thrombin is a "trypsin-like" serine protease that is encoded by the F2 gene in humans. Thrombin is produced by the enzymatic cleavage of two sites on prothrombin by activated Factor X (Xa). Thrombin in turn acts as a ser...		Others
T62688	Factor B-IN-4
	Factor B-IN-4 is a potent inhibitor (IC50: 1 μM) of complement factor B. Factor B-IN-4 can be used to study inflammatory and immune-related diseases.
T62292	Factor B-IN-2
	Factor B-IN-2 is a potent inhibitor (IC50: 1.5 μM) of complement factor B. Factor B-IN-2 can be used to study inflammatory and immune-related diseases.
T62276	Factor B-IN-3
	Factor B-IN-3 is a potent inhibitor of complement factor B. Factor B-IN-3 can be used to study inflammatory and immune-related diseases.
T62689	Factor B-IN-5
	Factor B-IN-5 is a potent inhibitor (IC50: 1.2 μM) of complement factor B. Factor B-IN-4 can be used to study inflammatory and immune-related diseases.
T0708	Oxaprozin	Oxaprozinum,Wy21743	NF-κB , COX
	Oxaprozin (Oxaprozinum) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of oxaprozin is as a Cyclooxygenase Inhibitor. The chemical classification of oxaprozin is Nonsteroidal Anti-inflammatory Compound...		NF-κB , COX
TD0099	Malachite green oxalate		Apoptosis , Others , IκB/IKK , NF-κB
	Malachite green oxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions.		Apoptosis , Others , IκB/IKK , NF-κB
T4335	GNE-617	GNE617	NAMPT
	GNE-617, a specific NAMPT inhibitor(IC50=5 nM), shows potency in xenograft models of cancer.		NAMPT
T39924	NF-κΒ activator 2		NF-κB
	NF-κΒ Activator 2 is a potent, orally active compound that efficiently activates NF-κB with an EC50 value of 1.58 μM. By enhancing NF-κB expression and activation, it induces SOD 2 synthesis, rendering it useful for amyo...		NF-κB
T12171	Nampt-IN-5		P450 , NAMPT
	Nampt-IN-5 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) .		P450 , NAMPT
T35570	Chiauranib	CS2164	c-Fms , VEGFR , FLT , PDGFR , c-Kit , Aurora Kinase
	Chiauranib is a multi-target inhibitor against tumor angiogenesis and exhibits potent anticancer effects. Chiauranib potently inhibits the angiogenesis-related kinases (VEGFR1, VEGFR2, VEGFR3, PDGFRα and c-Kit), mitosis-...		c-Fms , VEGFR , FLT , PDGFR , c-Kit , Aurora Kinase
T6682	STF-118804	STF 118804,STF118804	Apoptosis , NAMPT
	STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.		Apoptosis , NAMPT
T22450	Tyrphostin B44, (+) enantiomer		EGFR
	Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-) enantiomer.		EGFR
T4376	Nampt-IN-1	LSN3154567	c-Fms , NAMPT , CSF-1R
	Nampt-IN-1 (LSN3154567) (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.		c-Fms , NAMPT , CSF-1R
T4528	Tyrphostin AG 528	Tyrphostin B66,AG 528	EGFR
	Tyrphostin AG 528 (Tyrphostin B66) is an inhibitor of EGFR (IC50: 4.9 μM) and ErbB2 (IC50: 2.1 μM).		EGFR
T1998	CHS-828	CHS 828,GMX1778	Apoptosis , NAMPT
	CHS-828 (GMX1778), a pyridyl cyanoguanidine, is an effective inhibitor of NAD+ biosynthesis enzyme NAMPT (IC50 <25 nM).		Apoptosis , NAMPT
T25465	GS143	GS-143,GS 143	IκB/IKK , E1/E2/E3 Enzyme , NF-κB
	GS143 is a selective IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation. GS143 suppresses NF-κB activation and transcription of target genes and does not inhibit protea...		IκB/IKK , E1/E2/E3 Enzyme , NF-κB
T2600	AG490	Zinc02557947,Tyrphostin AG 490,AG 490,AG-490,Tyrphostin B42	EGFR , JAK , STAT , Autophagy
	AG490 (Tyrphostin B42) is an inhibitor of EGFR (IC50: 0.1 μM). It is 135-fold more selective for EGFR than ErbB2, also inhibits JAK2 with no effect to Lyn, Lck, Syk, Btk, and Src.		EGFR , JAK , STAT , Autophagy
T9189	Iptacopan hydrochloride	Iptacopan HCl,LNP023 hydrochloride	Complement System
	Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM. Iptacopan hydrochloride shows direct, reversible, and high-affinity b...		Complement System
T12854	SBI-797812		NAMPT
	SBI-797812 is structurally similar to active-site directed inhibitor of NAMPT(NAMPT with EC50 of 0.37 μM).		NAMPT
T12574	PTC299	Emvododstat,(4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate	VEGFR , Dehydrogenase
	PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNA translation and selectively inhibits VEGF protein synthesis at t...		VEGFR , Dehydrogenase
T41003	KG5		Raf , FLT , PDGFR , c-Kit
	KG5 is a dual allosteric inhibitor of PDGFRβ and B-Raf with a Kd of 520 nM and 300 nM for PDGFRβ and PDGFRα. KG5 inhibits FLT3, KIT, and c-Raf with anticancer and antiangiogenic activities.		Raf , FLT , PDGFR , c-Kit
T21312	Afatinib	Afatinib free base,BIBW 2992	EGFR , Autophagy
	Afatinib (BIBW 2992) is an irreversible inhibitor of EGFR family (EGFR-wt, EGFR-L858R, EGFR-L858R/T790M and HER2 with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM , respectively).		EGFR , Autophagy
T2644	(E)-Daporinad	Daporinad,(E)-N-[4-(1-BENZOYL-PIPERIDIN-4-YL)-BUTYL]-3-PYRIDIN-3-YL-ACRYLAMIDE,APO866,FK866	NAMPT , Transferase , Autophagy
	(E)-Daporinad (FK866) is a small molecule inhibitor of nicotinamide phosphoribosyltransferase (NMPRTase), with potential antineoplastic and antiangiogenic activities.		NAMPT , Transferase , Autophagy
T1773	Afatinib Dimaleate	BIBW2992,Afatinib,BIBW 2992MA2,Afatinib (BIBW2992) Dimaleate	EGFR , HER , Autophagy
	Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor receptor (ErbB; EGFR) family, with antineoplastic act...		EGFR , HER , Autophagy
T11864	Iptacopan	LNP023	Others
	Iptacopan (LNP023) is an inhibitor with high affinity for factor B.		Others
T7568	LM22A-4		Trk receptor
	LM22A-4 is a brain-derived neurotrophic factor (BDNF) mimetic and agonist of the receptor tropomyosin-related kinase B (TrkB; IC50 : 47 nM in a fluorescence anisotropy assay)		Trk receptor
T76957	Belimumab	LymphoStat B	TNF
	Belimumab(LymphoStat B) is a human IgG1λ monoclonal antibody that inhibits B-cell activating factor (BAFF).Belimumab is used in the study of fatigue and in the treatment of lupus nephritis and systemic lupus erythematosu...		TNF
T4182	Lavendustin B		Tyrosinase , transporter , HIV Protease
	Lavendustin B is a Tyrosine Kinase Inhibitor and an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived growth factor (LEDGF/p75).		Tyrosinase , transporter , HIV Protease
T3476	JI-101	CGI-1842,JI 101	VEGFR , PDGFR , Ephrin Receptor
	JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets vascular endothelial growth factor receptor type 2 (VEGFR-2), platelet derived growth factor receptor β (PDGFR-β), and ephrin type-B receptor 4 (EphB4).		VEGFR , PDGFR , Ephrin Receptor
T39392L	C-Type Natriuretic Peptide (CNP) (1-22), human acetate	C-Type Natriuretic Peptide (CNP) (1-22), human acetate(1966153-17-2 Free base)	Others
	C-Type Natriuretic Peptide (CNP) (1-22), human acetate is an agonist of natriuretic peptide receptor B (NPR-B), an endothelial-derived relaxant and growth inhibitory factor. C-Type Natriuretic Peptide (CNP) (1-22), huma...		Others
T60619	CDK9-IN-15		CDK
	CDK9-IN-15 is a potent small molecule CDK9 inhibitor, which can block the phosphorylation of positive transcription elongation factor b (P-TEFb) on the C-terminal region of RNA Poly-II by degradation and inhibition of CD...		CDK
T61822	M1002		HIF
	M1002 is a hypoxia-inducible factor-2 (HIF-2) agonist that enhances the affinity of HIF-2alpha and ARNT for transcriptional activation.M1002 alters the Tyr2 conformation of the HIF-281alpha PAS-B structural domain and ac...		HIF
T9659	LCB 03-0110	3-(2-(3-(Morpholinomethyl)phenyl)thieno[3,2-b]pyridin-7-ylamino)phenol	Discoidin Domain Receptor (DDR)
	LCB 03-0110 (3-(2-(3-(Morpholinomethyl)phenyl)thieno[3,2-b]pyridin-7-ylamino)phenol) is a potent inhibitor of discoidin domain receptor family tyrosine kinases and strongly inhibits several tyrosine kinases, including th...		Discoidin Domain Receptor (DDR)
T76830	Teneliximab	Chi220,Anti-Human CD40 Recombinant Antibody,BMS 224819	TNF
	Teneliximab (Chi220) is a chimeric monoclonal antibody and a tumor necrosis factor receptor superfamily member 5 (CD40) inhibitor that blocks CD40-CD40L interactions.Teneliximab exerts partial agonist activity through CD...		TNF
T22436	Takeda-6d		VEGFR
	Takeda-6d, a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor, inhibits B-RAF and VEGFR2 with IC50 of 7.0nM and 2.2nM.		VEGFR
T0983L	DL-Penicillamine	3-Sulfanylvaline	Antibiotic
	DL-Penicillamine (3-Sulfanylvaline) is a chelating agent recommended for the removal of excess copper in patients with Wilson's disease. DL-Penicillamine is only found in individuals that have used or taken this drug. It...		Antibiotic
T69628	Iptacopan hydrochloride hydrate
	Iptacopan hydrochloride hydrate is a highly potent and highly selective factor B inhibitor.
T32687	Leustroducsin B	LSN B
	Leustroducsin B is a novel colony-stimulating factor (CSF) inducer extracted from Streptomyces platensis SANK 60191.
T70563	KC-11404
	KC-11404 is an LTB4 inhibitor for the treatment of b-cell leukemias and lymphomas, potently inhibiting histamine, platelet activating factor and 5-lipoxygenase.
T10436L	AZD4573 HCl (2057509-72-3 free base)	AZD4573 hydrochloride,AZD4573,AZD4573 HCl,AZD-4573,AZD 4573
	AZD-4573 is a selective and short-acting inhibitor of the serine/threonine cyclin-dependent kinase 9, the catalytic subunit of the RNA polymerase II elongation factor positive transcription elongation factor b. It also h...
T33509	MS 8209	MS8209,MS-8209
	MS 8209 is an amphotericin B derivative has effects on on tumor necrosis factor alpha synthesis and human immunodeficiency virus replication in macrophages.
T81655	Nonacog alfa	BAX326,Coagulation Factor IX [Recombinant]
	Nonacog alfa (BAX326), a recombinant human factor IX, is utilized in the study of hemophilia B [1].
T26993	CGP 56999A	CGP56999A,CGP-56999A
	CGP 56999A is an antagonist of GABA(B) receptor, it enhances expression of brain-derived neurotrophic factor and attenuates dopamine depletion in the rat corpus striatum.
T27033	CKD-712	CKD 712,CKD712
	CKD-712 is a nuclear factor NF-kappa B inhibitor. CKD-712 suppressed MMP-9, but not MMP-2 and other NF-κB-regulated proteins involved in cancer metastasis such as VEGF. CKD-712 induced cell cycle arrest at G2M phase by s...
T82616	Dalcinonacog alfa	CB-2679d,ISU-304,DalcA
	Dalcinonacog alfa, a recombinant factor IX (FIX), is utilized in the research of Hemophilia B [1].
T69080	T1001
	T1001 is an antagonist of hypoxia-inducible factor-2α subunit (HIF-2α) which displaces residue M252 from inside the HIF-2α PAS-B pocket toward the ARNT subunit to weaken heterodimerization.
T75152	ARC19499
	ARC19499, an aptamer, inhibits the tissue factor pathway inhibitor (TFPI), facilitating clot initiation and propagation through the extrinsic pathway. It binds specifically to TFPI, blocking its inhibition of both factor...
T68755	NZ-28
	NZ28, also known as NSC134754, is potent HSF1 inhibitor, which induced inhibition of HSF1, SP1 and NF-κB triggers the loss of the natural killer cell-activating ligands MICA/B on human tumor cells. Heat-shock transcript...

Compounds

coagulation factor II (thrombin) B chain fragment [Homo sapiens]

Synonym: Oxaprozinum,Wy21743

Target: NF-κB, COX

Malachite green oxalate

TD0099

Synonym:

Target: Apoptosis, Others, IκB/IKK, NF-κB

Target: c-Fms, VEGFR, FLT, PDGFR, c-Kit, Aurora Kinase

STF-118804

T6682

Synonym: STF 118804,STF118804

Target: Apoptosis, NAMPT

Tyrphostin B44, (+) enantiomer

Target: c-Fms, NAMPT, CSF-1R

Tyrphostin AG 528

T4528

Synonym: Tyrphostin B66,AG 528

Target: EGFR

CHS-828

T1998

Synonym: CHS 828,GMX1778

Target: Apoptosis, NAMPT

GS143

T25465

Synonym: GS-143,GS 143

Target: IκB/IKK, E1/E2/E3 Enzyme, NF-κB

AG490

T2600

Synonym: Zinc02557947,Tyrphostin AG 490,AG 490,AG-490,Tyrphostin B42

Target: EGFR, JAK, STAT, Autophagy

Iptacopan hydrochloride

T9189

Synonym: Iptacopan HCl,LNP023 hydrochloride

Target: Complement System

Synonym: Emvododstat,(4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate

Target: VEGFR, Dehydrogenase

KG5

T41003

Synonym:

Target: Raf, FLT, PDGFR, c-Kit

Afatinib

T21312

Synonym: Afatinib free base,BIBW 2992

Target: EGFR, Autophagy

(E)-Daporinad

T2644

Synonym: Daporinad,(E)-N-[4-(1-BENZOYL-PIPERIDIN-4-YL)-BUTYL]-3-PYRIDIN-3-YL-ACRYLAMIDE,APO866,FK866

Target: NAMPT, Transferase, Autophagy

Afatinib Dimaleate

T1773

Synonym: BIBW2992,Afatinib,BIBW 2992MA2,Afatinib (BIBW2992) Dimaleate

Target: EGFR, HER, Autophagy

Synonym: LymphoStat B

Target: Tyrosinase, transporter, HIV Protease

JI-101

T3476

Synonym: CGI-1842,JI 101

Target: VEGFR, PDGFR, Ephrin Receptor

C-Type Natriuretic Peptide (CNP) (1-22), human acetate

T39392L

Synonym: C-Type Natriuretic Peptide (CNP) (1-22), human acetate(1966153-17-2 Free base)

Synonym: 3-(2-(3-(Morpholinomethyl)phenyl)thieno[3,2-b]pyridin-7-ylamino)phenol

Target: Discoidin Domain Receptor (DDR)

Teneliximab

T76830

Synonym: Chi220,Anti-Human CD40 Recombinant Antibody,BMS 224819

Synonym: 3-Sulfanylvaline

Target: Antibiotic

Iptacopan hydrochloride hydrate

AZD4573 HCl (2057509-72-3 free base)

T10436L

Synonym: AZD4573 hydrochloride,AZD4573,AZD4573 HCl,AZD-4573,AZD 4573

Target:

MS 8209

T33509

Synonym: MS8209,MS-8209

Target:

Nonacog alfa

T81655

Synonym: BAX326,Coagulation Factor IX [Recombinant]

Target:

CGP 56999A

T26993

Synonym: CGP56999A,CGP-56999A

Target:

CKD-712

T27033

Synonym: CKD 712,CKD712

Target:

Dalcinonacog alfa

T82616

Synonym: CB-2679d,ISU-304,DalcA

カタログ番号	製品名	別名	ターゲット
T3893	Forsythoside B		TNF , NF-κB
	Forsythoside B binds to LPS and reduces the biological activity of serum LPS, and inhibits NF-κB activation. Forsythoside B inhibits the inflammatory response and has antioxidant properties. Potent neuroprotective effect...		TNF , NF-κB
T1255	Tobramycin	NSC 180514,Nebramycin Factor 6,Deoxykanamycin B	ribosome , Antibacterial , Antibiotic
	Tobramycin (NSC-180514) is an aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius.		ribosome , Antibacterial , Antibiotic
T2734	Sennoside B		PDGFR
	Sennoside B is an anthranoid. Anthranoid derivatives are used all over the world as a treatment for constipation.		PDGFR
T7030	Anemarsaponin B		p38 MAPK , NF-κB , MEK , COX , NO Synthase
	Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity, possibly via the p38 MAP kinase pathway. Anemarsaponin B c...		p38 MAPK , NF-κB , MEK , COX , NO Synthase
T13265	Urolithin B		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
	Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical fruits, and medicinal herbs. Urolithin B inhibits NF-κB activit...		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
T6S0781	Phellodendrine	Phallodendrin	Others , NF-κB , Akt
	1. Phellodendrine (Phallodendrin) has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli.		Others , NF-κB , Akt
T2906	Tanshinone IIA	Tanshinone B,Dan Shen ketone	VEGFR
	Tanshinone IIA (Tanshinone B)(Tanshinone B) is the diterpene quinone in Danshen, which is utilized in the treatment of cardiovascular and inflammatory.		VEGFR
T0724	Formononetin	Biochanin B,Flavosil,Formononetol	Apoptosis , FGFR
	Formononetin (Flavosil) is an O-methylated isoflavone and a phytoestrogen from the root of Astragalus membranaceus.		Apoptosis , FGFR
T8846	beta-Escin	B-escin,AESCINE	Immunology/Inflammation related
	beta-Escin is a natural mixture of triterpenoid saponins isolated from horse chestnut (Aesculus hippocastanum) seeds, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent.		Immunology/Inflammation related
T17280	(Z)-Guggulsterone		Apoptosis , VEGFR , Akt
	(Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.		Apoptosis , VEGFR , Akt
TN1440	Beta-Hydroxyisovalerylshikonin		EGFR , Tyrosine Kinases , Prostaglandin Receptor , Src , AMPK , Fatty Acid Synthase
	Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor cell lines. Beta-Hydroxyisovalerylshikonin significantly de...
T3826	Polygalasaponin F		NF-κB , TLR , Akt , PI3K
	Polygalasaponin F has anti-neuroinflammatory activity, can inhibit the release of inflammatory cytokines TNF-α and NO induced by lipopolysaccharides (LPS) and reduce the expression of inducible nitric oxide synthases. Po...		NF-κB , TLR , Akt , PI3K
T0607	Dihydroartemisinin	β-Dihydroartemisinin,Dihydroqinghaosu,Artenimol,DHA	Apoptosis , NF-κB , Parasite , Autophagy
	Dihydroartemisinin (Artenimol) is a metabolite of artemisinin.		Apoptosis , NF-κB , Parasite , Autophagy
T2872	Ginsenoside Re	Ginsenoside B2,Panaxoside Re,Chikusetsusaponin Ivc,Sanchinoside Re	Beta Amyloid , NF-κB , Endogenous Metabolite , JNK
	Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.		Beta Amyloid , NF-κB , Endogenous Metabolite , JNK
T4S21320	ISOGINKGETIN	4',4'''-Dimethylamentoflavone	MMP , Others
	1. ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a known modulator of adiponecti...		MMP , Others
T3S0153	Xanthatin		Apoptosis , VEGFR , Lipoxygenase , Wnt/beta-catenin , Antibacterial
	1. Xanthatin has cytotoxic activity. 2. Xanthatin has antibacterial and antifungal activies against MRSA. 3. Xanthatin may have therapeutic potential against NSCLC. 4. Xanthatin can inhibit murine melanoma B16-F1 cell pr...
T2P2870	Damascenone	trans-damascenone,Beta-Damascenone	Others , NF-κB , Endogenous Metabolite
	Damascenone (trans-damascenone) is a norisoprenoid ketone mainly found in red wines. It occurs naturally in tomato and grapes.		Others , NF-κB , Endogenous Metabolite
T2775	Baicalin	Baicalein 7-O-β-D-glucuronide	NF-κB , HIV Protease , GABA Receptor , Autophagy
	Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV properties.		NF-κB , HIV Protease , GABA Receptor , Autophagy
TN1182	11-Keto-beta-boswellic acid	11-Keto-beta-boswellic acid	Leukotriene Receptor , NF-κB , Lipoxygenase
	11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor; it exerts dose dependent cardioprotective effect manifested by dose-dependent reduction in serum lactate dehydrogenas...		Leukotriene Receptor , NF-κB , Lipoxygenase
T6S2140	β-Anhydroicaritin	Anhydroicaritin,Beta-Anhydroicaritin	MMP , Others , TNF , Interleukin
	1. β-Anhydroicaritin exhibits immunosuppressive effect on the mouse macrophages stimulated by LPS. 2. β-Anhydroicaritin phytosomes can inhibit enhanced bone turnover induced by ovariectomy, improve BMD the biomechanical ...		MMP , Others , TNF , Interleukin
T3138	Astaxanthin	β-Carotene-4,4'-dione,Ovoester,AstaXin,AstaREAL,trans-Astaxanthin	Reactive Oxygen Species , PPAR
	Astaxanthin (trans-Astaxanthin) is a keto-carotenoid in the terpenes class of chemical compounds. It is classified as a xanthophyll but it is a carotenoid with no vitamin A activity. It is present in most red-colored aqu...		Reactive Oxygen Species , PPAR
T2932	Ginsenoside Rh1	Sanchinoside B2,Prosapogenin A2,20(S)-Ginsenoside Rh1,Sanchinoside Rh1	IL Receptor , TNF , Endogenous Metabolite , PPAR , Interleukin
	Ginsenoside Rh1 (Sanchinoside B2) , one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.
T1205	Chloramphenicol	Chlornitromycin,Levomycetin,Chloromycetin	ribosome , HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
	Chloramphenicol (Chloromycetin), a broad-spectrum antibiotic, blocks bacterial protein synthesis.
T2851	Daphnetin	7,8-Dihydroxycoumarin,Daphnetol	EGFR , PKA , PKC , Parasite , Autophagy
	Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-...		EGFR , PKA , PKC , Parasite , Autophagy
TN4222	Homoeriodictyol 7-O-β-D-glucoside	Homoeriodictyol 7-O-glucoside	Others , Platelet aggregation
	Homoeriodictyol 7-O-β-D-glucoside (Homoeriodictyol 7-O-glucoside) is a natural product from Viscum coloratum(Kom.)Nakai. Homoeriodictyol 7-O-β-D-glucoside is an antagonist of platelet-activating factor (PAF).		Others , Platelet aggregation
TN3209	3′,4′,7-Trihydroxyflavone		ATPase , Others , p38 MAPK , NF-κB
	3'4'7-Trihydroxyflavone can markedly inhibit the receptor activator of nuclear factor kappa B ligand (RANKL) induced osteoclastic differentiation from mouse bone marrow derived macrophages (BMMs), it inhibits osteoclasto...		ATPase , Others , p38 MAPK , NF-κB
T8852	Tubuloside B		Apoptosis , Others
	The neuroprotective effect of tubuloside B, one of the phenylethanoids isolated from the stems of Cistanche salsa, on tumor necrosis factor-alpha (TNFalpha)-induced apoptosis in SH-SY5Y neuronal cells.		Apoptosis , Others
T3892	Isoacteoside	Isoverbascoside	NF-κB
	Isoacteoside has the anti-inflammatory effect, mediated by action on caspase-1, mitogen-activated protein kinases (c-Jun N-terminal kinase, p38, extracellular signal-regulated protein kinase) and nuclear factor-kappa B p...		NF-κB
TWS1977	Kamebakaurin	Kamebakaurine	NF-κB
	1. Kamebakaurin (Kamebakaurine) has the ability to protect the liver from APAP-induced hepatotoxicity, presumably by both inhibiting the inflammatory response and oxidative stress. 2. Kamebakaurin inhibits the expression...		NF-κB
T6429	Caffeic Acid Phenethyl Ester	Phenylethyl Caffeate,CAPE	Apoptosis , NF-κB
	Caffeic Acid Phenethyl Ester (Phenylethyl Caffeate) (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways, with antineoplastic, cytoprotective...		Apoptosis , NF-κB
T2787	Picroside I	6'-Cinnamoylcatalpol	MMP , STAT
	Picroside I (6'-Cinnamoylcatalpol), a hepatoprotective agent, is reported to be antimicrobial and used against hepatitis B. It has antioxidant, and anti-inflammatory activities, it may be the valuable anti-invasive drug ...		MMP , STAT
T6S1256	Ruscogenin		NOS , NF-κB , NOD-like Receptor (NLR)
	1. Ruscogenin has anti-inflammatory activity, suppressed zymosan A-evoked peritoneal total leukocyte migration in mice in a dose-dependent manner, 2. Ruscogenin inhibited adhesion of leukocytes to a human umbilical vein ...		NOS , NF-κB , NOD-like Receptor (NLR)
T1040	Vitamin B12	Cyanocobalamin,Cobalamin	Endogenous Metabolite
	Cyanocobalamin is a cobalt-containing coordination compound generated by intestinal microbes and a natural water-soluble vitamin of the B-complex family that must combine with Intrinsic Factor for absorption by the intes...		Endogenous Metabolite
T0798	Triamcinolone	Fluoxyprednisolone,Aristocort,Rodinolone	Glucocorticoid Receptor , COX
	Triamcinolone (Aristocort) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. Upon cell entry, triamcinolone binds to and activates the glucocorticoid receptor, which leads to transloca...		Glucocorticoid Receptor , COX
T1331	Riboflavin phosphate sodium	Riboflavin 5'-phosphate sodium,Vitamin B2 Phosphate Sodium Salt,Flavin mononucleotide,FMN,FMN-Na,riboflavin-5'-phosphate	Endogenous Metabolite
	Riboflavin phosphate sodium (FMN) is the phosphate sodium salt form of riboflavin, a water-soluble and essential micronutrient that is the principal growth-promoting factor in naturally occurring vitamin B complexes. Rib...		Endogenous Metabolite
T73201	Stigmane B
	Stigmane B, a nuclear factor E2-related factor (Nrf2) activator, exhibits neuroprotective effects by downregulating apoptosis and reactive oxygen species (ROS) generation while increasing antioxidant enzyme activities.
T81814	Methyl Ganoderic acid B
	Methyl Ganoderic acid B, a triterpenoid isolated from Ganoderma lucidum, exhibits neuronal survival-promoting effects similar to nerve growth factor (NGF-like) [1].
TN1815	Kadsulignan L		HBV , PAFR
	Kadsulignan L shows in vitro antiviral effects on hepatitis B virus. It also shows moderate platelet-activating factor (PAF) antagonistic activities with the IC50 value of 2.6 x 10(-5) M.		HBV , PAFR
T38275	Kirromycin
	Kirromycin is an antibiotic originally isolated from Streptomyces and an inhibitor of protein biosynthesis. It inhibits isoleucine incorporation, polyphenylalanine synthesis, and growth of B. brevis. Kirromycin inhibits ...
T79948	Kadsurenin B
	Kadsurenin B, a platelet-activating factor (PAF) antagonist, exhibits neuroprotective properties and has a broad spectrum of pharmacological research applications, including antibacterial, anti-inflammatory, neuroprotect...
TN4126	Gentiside B		Others
	Gentiside B is a potent inducer of neurite outgrowth on PC12 cells, it shows a significant neuritogenic activity at 30 microM against PC12 cells that is comparable to that seen for the best nerve growth factor (NGF) conc...		Others
T75485	Dehydrobruceine B
	Dehydrobruceine B, a quassinoid isolated from Brucea javanica, demonstrates a synergistic effect with Cisplatin in inducing apoptosis through the mitochondrial pathway. It enhances the expression of apoptosis-inducing fa...
TN3706	Coronarin A
	Coronarin, A, B, C, and D are cytotoxic prinicples from the rhizomes of Hedychium coronarium, Zingiberaceae. Coronarin A exhibits good growth inhibition activities on HUVEC proliferation, it effectively suppresses the gr...
TN4190	Hedycoronen A		IL Receptor , TNF
	Hedycoronen A and hedycoronen B have the potential anti-inflammatory benefits, they are potent inhibitors of LPS-stimulated interleukin-6 (IL-6) and IL-12 p40, with IC(50) ranging from 4.1±0.2 to 9.1±0.3 uM, they also sh...		IL Receptor , TNF
T36439	Gramicidin A		Antibacterial , HIF , Parasite
	Gramicidin A is a peptide antibiotic isolated from B. brevis.Gramicidin A is a highly hydrophobic channel-forming ion carrier that forms monovalent cation-permeable channels in artificial membranes.Gramicidin A induces t...		Antibacterial , HIF , Parasite
TN2217	Sophoflavescenol		Others , Beta-Secretase , BACE , PDE , AChR , AChE
	Sophoflavescenol is a mixed inhibitor of PDE5 with a K(i) value of 0.005 microM. Sophoflavescenol has antioxidant, anti-inflammatory, and apoptotic effects , these effects might contribute to the antitumor activity witho...		Others , Beta-Secretase , BACE , PDE , AChR , AChE

天然物製品

Synonym: NSC 180514,Nebramycin Factor 6,Deoxykanamycin B

Target: ribosome, Antibacterial, Antibiotic

Target: p38 MAPK, NF-κB, MEK, COX, NO Synthase

Urolithin B

T13265

Synonym:

Target: ERK, NF-κB, Akt, Endogenous Metabolite, JNK, AMPK

Phellodendrine

T6S0781

Synonym: Phallodendrin

Target: Others, NF-κB, Akt

Tanshinone IIA

T2906

Synonym: Tanshinone B,Dan Shen ketone

Target: VEGFR

Formononetin

T0724

Synonym: Biochanin B,Flavosil,Formononetol

Target: Apoptosis, FGFR

beta-Escin

T8846

Synonym: B-escin,AESCINE

Target: Immunology/Inflammation related

(Z)-Guggulsterone

T17280

Synonym:

Target: Apoptosis, VEGFR, Akt

Beta-Hydroxyisovalerylshikonin

TN1440

Synonym:

Target: EGFR, Tyrosine Kinases, Prostaglandin Receptor, Src, AMPK, Fatty Acid Synthase

Polygalasaponin F

T3826

Synonym:

Target: NF-κB, TLR, Akt, PI3K

Dihydroartemisinin

T0607

Synonym: β-Dihydroartemisinin,Dihydroqinghaosu,Artenimol,DHA

Target: Apoptosis, NF-κB, Parasite, Autophagy

Ginsenoside Re

T2872

Synonym: Ginsenoside B2,Panaxoside Re,Chikusetsusaponin Ivc,Sanchinoside Re

Target: Beta Amyloid, NF-κB, Endogenous Metabolite, JNK

ISOGINKGETIN

T4S21320

Synonym: 4',4'''-Dimethylamentoflavone

Target: Apoptosis, VEGFR, Lipoxygenase, Wnt/beta-catenin, Antibacterial

Damascenone

T2P2870

Synonym: trans-damascenone,Beta-Damascenone

Target: Others, NF-κB, Endogenous Metabolite

Baicalin

T2775

Synonym: Baicalein 7-O-β-D-glucuronide

Target: NF-κB, HIV Protease, GABA Receptor, Autophagy

11-Keto-beta-boswellic acid

TN1182

Synonym: 11-Keto-beta-boswellic acid

Target: Leukotriene Receptor, NF-κB, Lipoxygenase

β-Anhydroicaritin

T6S2140

Synonym: Anhydroicaritin,Beta-Anhydroicaritin

Target: MMP, Others, TNF, Interleukin

Astaxanthin

T3138

Synonym: β-Carotene-4,4'-dione,Ovoester,AstaXin,AstaREAL,trans-Astaxanthin

Target: Reactive Oxygen Species, PPAR

Ginsenoside Rh1

T2932

Synonym: Sanchinoside B2,Prosapogenin A2,20(S)-Ginsenoside Rh1,Sanchinoside Rh1

Target: IL Receptor, TNF, Endogenous Metabolite, PPAR, Interleukin

Chloramphenicol

T1205

Synonym: Chlornitromycin,Levomycetin,Chloromycetin

Target: ribosome, HIF/HIF Prolyl-Hydroxylase, Antibacterial, Antibiotic

Daphnetin

T2851

Synonym: 7,8-Dihydroxycoumarin,Daphnetol

Target: EGFR, PKA, PKC, Parasite, Autophagy

Homoeriodictyol 7-O-β-D-glucoside

TN4222

Synonym: Homoeriodictyol 7-O-glucoside

Target: Others, Platelet aggregation

3′,4′,7-Trihydroxyflavone

TN3209

Synonym:

Target: ATPase, Others, p38 MAPK, NF-κB

tubuloside B

T8852

Synonym:

Target: Apoptosis, Others

Isoacteoside

T3892

Synonym: Isoverbascoside

Target: NF-κB

Kamebakaurin

TWS1977

Synonym: Kamebakaurine

Target: NF-κB

Caffeic Acid Phenethyl Ester

T6429

Synonym: Phenylethyl Caffeate,CAPE

Target: Apoptosis, NF-κB

Picroside I

T2787

Synonym: 6'-Cinnamoylcatalpol

Target: NOS, NF-κB, NOD-like Receptor (NLR)

Vitamin B12

T1040

Synonym: Cyanocobalamin,Cobalamin

Target: Endogenous Metabolite

Triamcinolone

T0798

Synonym: Fluoxyprednisolone,Aristocort,Rodinolone

Target: Glucocorticoid Receptor, COX

Riboflavin phosphate sodium

T1331

Synonym: Riboflavin 5'-phosphate sodium,Vitamin B2 Phosphate Sodium Salt,Flavin mononucleotide,FMN,FMN-Na,riboflavin-5'-phosphate

Target: Endogenous Metabolite

Methyl Ganoderic acid B

Target: IL Receptor, TNF

Gramicidin A

T36439

Synonym:

Target: Antibacterial, HIF, Parasite

Sophoflavescenol

TN2217

Synonym:

Target: Others, Beta-Secretase, BACE, PDE, AChR, AChE

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-02185	Coagulation factor XIII B/F13B Protein, Human, Recombinant (His)	Human	HEK293
	Coagulation factor XIII B chain, also known as Fibrin-stabilizing factor B subunit, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain and F13B, is a secreted protein which contains 1 Sushi ...
TMPY-04921	Complement factor B/CFB Protein, Human, Recombinant (His)	Human	HEK293
	Complement factor B/CFB Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 84.5 kDa. Accession number: AAH04143.1
TMPH-02607	Complement factor B Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convert...
TMPJ-00662	RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)	Human	E. coli
	CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL i...
TMPY-03221	Intrinsic Factor Protein, Human, Recombinant (His)	Human	HEK293
	Gastric intrinsic factor, also known as GIF, belongs to the of the cobalamin transport protein family. It is a glycoprotein produced by the parietal cells of the stomach. Gastric intrinsic factor plays a key role in the ...
TMPJ-00607	RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Mouse tumor necrosis factor ligand superfamily member 11(Tnfsf11) is a member of the tumor necrosis factor (TNF) cytokine family. Tnfsf11 is widely expressed in cells including T cells and T cell rich organs, such as thy...
TMPJ-00035	IL-4 Protein, Human, Recombinant (His)	Human	Human Cells
	Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal ce...
TMPJ-01391	BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc)	Mouse	Human Cells
	TNFSF13B/TNFSF20 belongs to the tumor necrosis factor family. It abundantly is expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bo...
TMPY-03945	Latent TGF beta 1 Protein, Rat, Recombinant (His)	Rat	HEK293
	TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-04211	Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-00608	TGF beta 1 Protein, Rat/Mouse, Recombinant	Mouse,Rat	HEK293
	TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPJ-01469	NGF Protein, Human, Recombinant (E. colli)	Mouse	E.coli
	NGF is the first member discovered in the Neurotrophin family, which includes brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). These proteins belong to the cysteine-knot family ...
TMPY-02638	TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant	Human,Rhesus,Cynomolgus,Canine	CHO
	TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPJ-01468	Pro-Beta NGF Protein, Human, Recombinant	Human	E.coli
	The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite...
TMPY-01010	NGF Protein, Human, Recombinant	Human	CHO
	NGF Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 13.2 kDa and the accession number is P01138.
TMPY-06985	NGF Protein, Human, Recombinant (HEK293)	Human	HEK293
	Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits,...
TMPJ-00254	TGF beta 3 Protein, Human/Mouse/Rat, Recombinant	Human,Mouse,Rat	Human Cells
	Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes acti...
TMPY-01133	Latent TGF beta 1 Protein, Human, Recombinant (His)	Human	HEK293
	TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-06247	TGF beta 3 Protein, Human, Recombinant (hFc)	Human	HEK293
	TGF beta 3 Protein, Human, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 41.2 kDa. Accession number: P10600-1
TMPJ-00249	TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated	Human	Human Cells
	Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-...
TMPY-00500	Latent TGF beta 1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-00413	TGF beta 2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a...
TMPJ-00258	TGF beta 2 Protein, Human, Recombinant	Human	Human Cells
	Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. T...
TMPY-04644	PDGFB Protein, Human, Recombinant (His)	Human	Yeast
	Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit...
TMPJ-00261	TGF beta 2 Protein, Mouse/Rat, Recombinant	Mouse,Rat	Human Cells
	Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofaci...
TMPJ-00994	LTBR Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	It is a single-pass type I membrane protein and contains 4 TNFR-Cys repeats. The protein is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including ce...
TMPJ-00335	TGFBR2 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β regulates cellular processes by binding to three high-affinit...
TMPY-01009	TGFBI Protein, Human, Recombinant (His)	Human	HEK293
	TGFBI is an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several ...
TMPY-05157	TGFBR2 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma...
TMPH-03532	ClfB Protein, S. aureus (strain MRSA252), Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps.
TMPJ-00968	NAMPT Protein, Human, Recombinant (His)	Human	E. coli
	Pre-B cell colony enhancing factor (PBEF) was originally identified as a cytokine that potentiated the clonal expansion and differentiation of pre-B cells, but it is also acknowledged to be the ubiquitous intracellular e...
TMPY-04327	VEGFB Protein, Human, Recombinant (hFc)	Human	HEK293
	Vascular endothelial growth factor-B (VEGF-B) is closely related to VEGF-A, an effector of blood vessel growth during development and disease and a strong candidate for angiogenic therapies. In detail, VEGFB can positive...
TMPY-04877	PDGFB Protein, Mouse, Recombinant (His)	Mouse	Yeast
	Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit...
TMPJ-00020	IL-5 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	Human Cells
	IL-5 is expressed in eosinophils, NK cells, TC2 CD8+ T cells, mast cells, CD45+ CD4+ T cells, gamma delta T cells and IL-1 beta activated endothelial cells. IL-5 acts as a growth and differentiation factor for both B cel...
TMPJ-00887	NFKB1 Protein, Human, Recombinant (His)	Human	E. coli
	The 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radica...
TMPJ-00472	Vitronectin Protein, Human, Recombinant (Truncated, His)	Human	Human Cells
	Vitronectin, also known as VTN, is a large glycoprotein found in blood and the extracellular matrix (ECM). Vitronectin is a plasma glycoprotein implicated as a regulator of diverse physiological process, including blood ...
TMPY-03504	CBFB Protein, Human, Recombinant (His)	Human	E. coli
	CBFB is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and os...
TMPJ-00178	BAFF/TNFSF13B Protein, Human, Recombinant (His)	Human	Human Cells
	TNFSF13B/TNFSF20 belongs to the tumor necrosis factor family. It abundantly is expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bo...
TMPJ-00034	IL-4 Protein, Human, Recombinant (hFc)	Human	Human Cells
	Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal ce...
TMPH-01457	Human herpesvirus 6B (HHV-6 variant B) (strain Z29) mRNA export factor ICP27 homolog (His & Myc)	HHV-6B	E. coli
	Human herpesvirus 6B (HHV-6 variant B) (strain Z29) mRNA export factor ICP27 homolog (His & Myc) is expressed in E. coli.
TMPY-01710	IkB alpha/NFKBIA Protein, Human, Recombinant (His)	Human	E. coli
	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (IkB alpha, NFKBIA, or IKBA), is a member of the NF-kappa-B inhibitor family that function to inhibit the NF-kB transcription factor. NF...
TMPY-00229	Latent TGF beta 1 Protein, Canine, Recombinant (His)	Canine	HEK293
	TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-04577	TGF beta 2 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a...
TMPY-03649	TGFBR3 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Betaglycan also known as transforming growth factor beta receptor III (TGFBR3), is a cell-surface chondroitin sulfate / heparan sulfate proteoglycan. TGFBR3 is a transforming growth factor (TGF)-beta type III receptor. T...
TMPY-01402	NGF Protein, Mouse, Recombinant	Mouse	CHO
	Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits,...
TMPY-03171	TGFBR2 Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293
	TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma...
TMPY-03082	TGFBR2 Protein, Rat, Recombinant (hFc)	Rat	HEK293
	TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma...
TMPJ-00349	RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)	Human	Human Cells
	Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANK...
TMPY-05076	PDGFB Protein, Canine, Recombinant (His)	Canine	Yeast
	Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit...
TMPY-05077	PDGFB Protein, Rhesus, Recombinant (His)	Rhesus	Yeast
	Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit...
------------------------ More ------------------------

Coagulation factor XIII B/F13B Protein, Human, Recombinant (His)

TMPY-02185

Species: Human

Expression System: HEK293

Complement factor B/CFB Protein, Human, Recombinant (His)

TMPY-04921

Species: Human

Expression System: HEK293

Complement factor B Protein, Mouse, Recombinant (His)

TMPH-02607

Species: Mouse

Expression System: E. coli

RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)

TMPJ-00662

Species: Human

Expression System: E. coli

Intrinsic Factor Protein, Human, Recombinant (His)

TMPY-03221

Species: Human

Expression System: HEK293

RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)

TMPJ-00607

Species: Mouse

Expression System: Human Cells

IL-4 Protein, Human, Recombinant (His)

TMPJ-00035

Species: Human

Expression System: Human Cells

BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc)

TMPJ-01391

Species: Mouse

Expression System: Human Cells

Latent TGF beta 1 Protein, Rat, Recombinant (His)

TMPY-03945

Species: Rat

Expression System: HEK293

Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)

TMPY-04211

Species: Cynomolgus

Expression System: HEK293

TGF beta 1 Protein, Rat/Mouse, Recombinant

TMPY-00608

Species: Mouse,Rat

Expression System: HEK293

NGF Protein, Human, Recombinant (E. colli)

TMPJ-01469

Species: Mouse

Expression System: E.coli

TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant

TMPY-02638

Species: Human,Rhesus,Cynomolgus,Canine

Expression System: CHO

pro-Beta NGF Protein, Human, Recombinant

TMPJ-01468

Species: Human

Expression System: E.coli

NGF Protein, Human, Recombinant

TMPY-01010

Species: Human

Expression System: CHO

NGF Protein, Human, Recombinant (HEK293)

TMPY-06985

Species: Human

Expression System: HEK293

TGF beta 3 Protein, Human/Mouse/Rat, Recombinant

TMPJ-00254

Species: Human,Mouse,Rat

Expression System: Human Cells

Latent TGF beta 1 Protein, Human, Recombinant (His)

TMPY-01133

Species: Human

Expression System: HEK293

TGF beta 3 Protein, Human, Recombinant (hFc)

TMPY-06247

Species: Human

Expression System: HEK293

TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated

TMPJ-00249

Species: Human

Expression System: Human Cells

Latent TGF beta 1 Protein, Mouse, Recombinant (His)

TMPY-00500

Species: Mouse

Expression System: HEK293

TGF beta 2 Protein, Mouse, Recombinant (His)

TMPY-00413

Species: Mouse

Expression System: HEK293

TGF beta 2 Protein, Human, Recombinant

TMPJ-00258

Species: Human

Expression System: Human Cells

PDGFB Protein, Human, Recombinant (His)

TMPY-04644

Species: Human

Expression System: Yeast

TGF beta 2 Protein, Mouse/Rat, Recombinant

TMPJ-00261

Species: Mouse,Rat

Expression System: Human Cells

LTBR Protein, Mouse, Recombinant (hFc)

TMPJ-00994

Species: Mouse

Expression System: Human Cells

TGFBR2 Protein, Mouse, Recombinant (His)

TMPJ-00335

Species: Mouse

Expression System: Human Cells

TGFBI Protein, Human, Recombinant (His)

TMPY-01009

Species: Human

Expression System: HEK293

TGFBR2 Protein, Human, Recombinant (His)

TMPY-05157

Species: Human

Expression System: Baculovirus-Insect Cells

ClfB Protein, S. aureus (strain MRSA252), Recombinant (His & SUMO)

TMPH-03532

Species: Staphylococcus aureus

Expression System: E. coli

NAMPT Protein, Human, Recombinant (His)

TMPJ-00968

Species: Human

Expression System: E. coli

VEGFB Protein, Human, Recombinant (hFc)

TMPY-04327

Species: Human

Expression System: HEK293

PDGFB Protein, Mouse, Recombinant (His)

TMPY-04877

Species: Mouse

Expression System: Yeast

IL-5 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPJ-00020

Species: Human

Expression System: Human Cells

NFKB1 Protein, Human, Recombinant (His)

TMPJ-00887

Species: Human

Expression System: E. coli

Vitronectin Protein, Human, Recombinant (Truncated, His)

TMPJ-00472

Species: Human

Expression System: Human Cells

CBFB Protein, Human, Recombinant (His)

TMPY-03504

Species: Human

Expression System: E. coli

BAFF/TNFSF13B Protein, Human, Recombinant (His)

TMPJ-00178

Species: Human

Expression System: Human Cells

IL-4 Protein, Human, Recombinant (hFc)

TMPJ-00034

Species: Human

Expression System: Human Cells

Human herpesvirus 6B (HHV-6 variant B) (strain Z29) mRNA export factor ICP27 homolog (His & Myc)

TMPH-01457

Species: HHV-6B

Expression System: E. coli

IkB alpha/NFKBIA Protein, Human, Recombinant (His)

TMPY-01710

Species: Human

Expression System: E. coli

Latent TGF beta 1 Protein, Canine, Recombinant (His)

TMPY-00229

Species: Canine

Expression System: HEK293

TGF beta 2 Protein, Rhesus, Recombinant (His)

TMPY-04577

Species: Rhesus

Expression System: HEK293

TGFBR3 Protein, Human, Recombinant (His)

TMPY-03649

Species: Human

Expression System: Baculovirus-Insect Cells

NGF Protein, Mouse, Recombinant

TMPY-01402

Species: Mouse

Expression System: CHO

TGFBR2 Protein, Rhesus, Recombinant (hFc)

TMPY-03171

Species: Rhesus

Expression System: HEK293

TGFBR2 Protein, Rat, Recombinant (hFc)

TMPY-03082

Species: Rat

Expression System: HEK293

RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)

TMPJ-00349

Species: Human

Expression System: Human Cells

PDGFB Protein, Canine, Recombinant (His)

TMPY-05076

Species: Canine

Expression System: Yeast

PDGFB Protein, Rhesus, Recombinant (His)

TMPY-05077

Species: Rhesus

Expression System: Yeast

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カタログ番号	製品名
L2193	Anti-Liver Cancer Compound Library	1787 compounds
	1787 species of compounds related to liver cancer that can be used in anti-liver cancer drug development and pharmacological studies.
L9830	Anti-Parkinson's Disease Compound Library	857 compounds
	A unique collection of 857 compounds with anti-PD activities or acting on main drug targets of PD can be used for HTS and HCS.
L2191	Anti-Breast Cancer Compound Library	1939 compounds
	A unique collection of 1939 compounds with anti-breast cancer therapeutic activity or targeting breast cancer’s major signaling pathways, can be used for anti-breast cancer drug discovery and mechanism study；
L3800	NF-κB Signaling Compound Library	729 compounds
	A unique collection of 729 compounds targeting NF-κB signaling for high throughput screening and high content screening;
L2550	Glutamine Metabolism Compound Library	565 compounds
	A unique collection of 565 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and ...

ライブラリー

Anti-Liver Cancer Compound Library

L2193

Compounds: 1787

Anti-Parkinson's Disease Compound Library

L9830

Compounds: 857

Anti-Breast Cancer Compound Library

L2191

Compounds: 1939

NF-κB Signaling Compound Library

L3800

Compounds: 729

Glutamine Metabolism Compound Library

L2550

Compounds: 565